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This was well illustrated at Vipery, in a situation abounding- with stagnant water, the receptacle of every species of filth, but more especially at the spot, where I strongly suspect the epidemic first broke out at Madras, and where many fell victims to its severity; for, it was observed to be more prevalent amongst, and indeed for the first two or three days almost exclusively confined to, the natives residing in some huts, about which much offensive and corrupted matter had been accumulated, while those occupying the houses almost contiguous suffered but slightly, though comparatively more, than the inhabitants in the adjacent and more distant streets."! Coutts, then in the Roads, became the subjects of the disease, but it upon deck, and those who slept to the landward side of the ship, were in both vessels decidedly the most obnoxious to the attacks of These and a multitude of other similar instances that might be adduced, would, in 50 the absence of facts of an opposite character, be conclusive as to the miasmatic origin of cholera, J and at least seem to show that malaria has some agency in its production. Mt - assistant Attending Physicist, Perelman, Michael A.